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3D organotypic cultures of human HepaRG cells, a tool for in vitro toxicity studies

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Activity on the NFAT signaling pathway of MC4R was also demonstrated, believed to be through the recruitment of G q , with superior potencies compared to -MSH and LY2112688

The SAM also participates in the synthesis of phosphatidylcholine, the major phospholipid found in mammalian cells (Vance and Tasseva, 2013)